Molecular Details
DICL_CP_0320875
- 4-chloro-N-(furan-2-ylmethyl)benzenesulfonamide
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0320875
PubChem CID
Molecular Formula
C11H10ClNO3S Molecular Weight
271.725 g/mol
Synonyms/Alias
[196813-49-7; 4-chloro-N-(2-furylmethyl)benzenesulfonamide; 4-chloro-N-[(furan-2-yl)methyl]benzene-1-sulfonamide; 4-chloro-N-(furan-2-ylmethyl)benzenesulfonamide; SCHEMBL25248439; HMS1674L15; 4-chloro...
InChI Key
HVMUXVUZSPFNQZ-UHFFFAOYSA-N
InChI
InChI=1S/C11H10ClNO3S/c12-9-3-5-11(6-4-9)17(14,15)13-8-10-2-1-7-16-10/h1-7,13H,8H2
IUPAC Name
4-chloro-N-(furan-2-ylmethyl)benzenesulfonamide
CAS Number
196813-49-7
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
27 28 0 0 0 0 0 0 0 0999 V2000
3.9685 1.7538 -0.2637 C 0 0 0 0 0 0 0 0 0 0 0 0
4.6136 0.6881 -0.8593 C 0 0 0 0 0 0 0 0 0 0 0 0
3.7409 -0.246...
Experimental Data
Activity Data
Target Ion Channel
Voltage-gated potassium channel subfamily C member 1
Uniprot Accession Number
Function
Blocker
Species
Homo sapiens (Human)
IC50
IC50: 53100 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
−88 to 32 mV mV
Temperature
37 °C
Test Method
Patch-clamping
Test Species
Not specified
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
17
Rotatable Bonds
4
logP
2.4115
Complexity
64.1855
TPSA (Ų)
59.31
H-Bond Donors
1
H-Bond Acceptors
3
Ring Count
2